Failure of Splenectomy to Ameliorate Portal Hypertension in Myeloproliferative Disorders

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[Pulmonary hypertension in chronic myeloproliferative disorders].

We report on three autopsy cases with clinical and morphological evidence of pulmonary hypertension and concurrent myeloproliferative disorders. Massive accumulations of pleomorphic, atypical megakaryocytes and thrombotic material are found within the pulmonary capillary beds. Morphometrical studies allowed us to identify on average 1,293.4 (1,145.8-1,401) megakaryocytes per one square centimet...

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Pulmonary vascular disorders in portal hypertension.

The wide spectrum of pulmonary vascular disorders in liver disease and portal hypertension ranges from the hepatopulmonary syndrome characterized by intrapulmonary vascular dilatations, to pulmonary hypertension (portopulmonary hypertension), in which pulmonary vascular resistance is elevated. Since hepatopulmonary syndrome and portopulmonary hypertension have been reported in patients with non...

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Portal Hypertension and Myeloproliferative Neoplasms: A Relationship Revealed

Background/Objectives. Patients with myeloproliferative neoplasms have a well-established increased risk of thrombosis. Many trials report identification of an underlying myeloproliferative neoplasm by investigation of the patients developing portal hypertensive esophagus and/or fundus variceal hemorrhage in the absence of any known etiology. This trial was designed to investigate the associati...

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ژورنال

عنوان ژورنال: Canadian Journal of Gastroenterology

سال: 1994

ISSN: 0835-7900

DOI: 10.1155/1994/632862